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The author of the book "Cosmic Serpent", Jeremy Narby, asked indigenous tribal people how they were able to first brew Ayahuasca. He was amazed that tribal people who had no information about botany or microbiology could select just two plants out of 70,000 plants in the Amazon; so he asked them, "How did you know which plants to use?" "The plants told us", they replied. The spirit of nature that is in all things is sentient. Plants and nature have a collective consciousness and intention that is beyond anything we can understand. It is beyond the scope of human mind.
One of the things that is currently happening with the sacred plant medicine called Ayahuasca, is that it is reaching out to humans, in order to heal them and make them whole. It is reaching out to help humans 'come across' to a whole new evolution. I just started reading Sting's new autobiography entitled, Broken Music and was amazed to find that chapter one contained a very detailed and beautiful account of his experience with Ayahuasca in Brazil.